Lamotrigine Tablets: Formulation and in Vitro Evaluation of Lamotrigine Orally Disintegrating Tablets and Sustained Release Tablets

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizures. While traditional anticonvulsant drugs are primarily antimanics, lamotrigine is the most effective drug in the treatment and prophylaxis of bipolar depression. Two novel drug delivery systems were prepared with Lamotrigine. Orally disintegrating tablets are useful for pediatric and geriatric patients as well as patients who are unable to swallow. ODTs provide an immediate action of controlling the emergency. while sustained release tablets (SRT) offer the advantages of reduced dosage frequency. It provide prolong drug action. In this project both the ODT and SRT of lamotrigine has prepared by simple method to serve the different conditions in epilepsy.