Cell Surface Receptors: A Short Course on Theory and Methods - Lee E. Limbird - Knjige - Springer-Verlag New York Inc. - 9781475718843 - 21. marca 2013
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Lee E. Limbird
Cell Surface Receptors: A Short Course on Theory and Methods Softcover reprint of the original 1st ed. 1986 edition

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The purpose of this book is to serve as a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying prin­ ciples is intended to remove the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, it is hoped that the basic concepts can be emphasized. This book is meant to be a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed. I feit compelled to write this book for several reasons. The primary philosophical reason was to provide, in one volume, an overall perspective on the study ofcell surface receptors that describes their characterization from pharmacological studies in a whole organ or tissue bath (chapter 2) to studies of radioligand binding in isolated membrane and detergent-solubilized pre­ parations (chapters 3-5) and, back again, to studies in intact cells or tissues using morphological and biochemical techniques (chapter 6). It is my opinion that the ultimate understanding of the molecular basis for hormone or drug­ receptor interactions, and the physiological consequences of these inter­ actions, will require an assessment of cell surface receptor function at all of these experimental levels. In many cases an investigator may not choose to of investigation considered here.

196 pages, 8 black & white illustrations, biography

Medij Knjige     Paperback Book   (Knjiga z mehkimi platnicami in lepljenim hrbtom)
Izdano 21. marca 2013
ISBN13 9781475718843
Založniki Springer-Verlag New York Inc.
Strani 196
Dimenzije 155 × 235 × 12 mm   ·   308 g
Jezik Angleščina  

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